Evidence Synthesis & Research Methodology Experts
Every Service From Protocol to Published Manuscript
Protocol, search, screening, extraction, risk of bias, statistics, and a publish-ready manuscript formatted to your target journal or committee. Led by PhD methodologists with peer-reviewed publication records. PRISMA 2020 and Cochrane Handbook methodology. Authorship stays with you.
Most Popular
Systematic Review
A comprehensive, reproducible synthesis of all available evidence addressing a clearly formulated research question. Our team follows Cochrane Handbook methodology and PRISMA 2020 reporting guidelines to deliver a publish-ready manuscript customized for your target journal, with unlimited revisions on every project.
What's Included
- Protocol development (PRISMA-P) & PROSPERO-ready protocol
- Comprehensive search across PubMed, Embase, Cochrane CENTRAL, Scopus, and more
- Title & abstract screening (dual reviewer)
- Full-text screening with documented exclusion reasons
- Data extraction table design & standardized forms
- Risk of bias assessment (RoB 2 / ROBINS-I / NOS)
- Narrative review structuring with summary of findings tables
- PRISMA 2020 flow diagram
- Medical manuscript drafting customized for your target Q1–Q4 journal
Typical timeline: 1 to 5 weeks (varies by delivery speed)
Scoping Review
Map the breadth of literature on a topic to identify key concepts, evidence gaps, and research trends. Ideal for emerging fields, grant proposals, and doctoral theses. Conducted per JBI methodology and reported using PRISMA-ScR guidelines.
What's Included
- Research question refinement (PCC framework)
- Search strategy across PubMed, Scopus, CINAHL, and discipline-specific databases
- Title & abstract screening
- Full-text screening with charting
- Data charting / extraction
- Thematic analysis of findings
- Evidence gap map
- PRISMA-ScR flow diagram
- Publish-ready summary report or manuscript draft
Typical timeline: 1 to 5 weeks (varies by delivery speed)
Meta-Analysis
Clinical research statistical consulting and data analysis for medical research. Quantitative pooling of effect sizes using R or Stata, forest plots, heterogeneity assessment, statistical interpretation, and publish-ready figures with fully reproducible code provided.
What's Included
- Effect size calculation and standardization
- Heterogeneity assessment (I², τ², prediction intervals)
- Fixed-effects and random-effects models
- Forest plots for all outcomes
- Subgroup and sensitivity analyses
- Leave-one-out analyses
- Funnel plots and Egger's test for publication bias
- Meta-regression (if applicable)
- GRADE certainty of evidence tables
Typical timeline: 1 to 5 weeks (varies by delivery speed)
Complete Package
Systematic Review + Meta-Analysis
Our most comprehensive package combines a full systematic review with quantitative meta-analysis. One flat price, no add-ons needed. Includes everything from both the Systematic Review and Meta-Analysis packages above.
Custom Quote
1 to 5 weeks (varies by delivery speed)
Custom Service / Inquiry
Need an umbrella review, narrative review structuring, individual components, or bespoke research methodology consulting? Describe your project and receive a personalized quote.
Research Support Services
Manuscript drafting, biostatistics consulting, grant methodology, and reviewer response. Available standalone or alongside any review project. Custom-quoted based on your specific needs.
Medical Manuscript Drafting
Custom Quote
Publish-ready manuscript (Introduction, Methods, Results, Discussion) written from your data, formatted to your target journal's specifications, reporting guidelines (CONSORT, STROBE, PRISMA), and citation style.
What's Included
- Full IMRAD manuscript structure
- Target journal formatting & word count compliance
- Reporting guideline adherence (CONSORT, STROBE, etc.)
- Tables, figure legends, and supplementary materials
- Reference management and citation formatting
- Cover letter draft for journal submission
- Unlimited revisions
Typical timeline: 1 - 4 weeks
Biostatistics & Study Design Consulting
Custom Quote
Clinical research statistical consulting and data analysis for medical research, whether you need standalone biostatistics consulting or statistical support integrated into your review project.
What's Included
- Statistical interpretation service for your results
- Study design consulting & sample size calculation
- Meta-regression & moderator analysis
- Heterogeneity assessment (I², τ², Q statistic)
- Publication bias testing (Egger's, trim-and-fill)
- Fully reproducible R or Stata code
Typical timeline: 1 - 3 weeks
Grant Methodology Service
Custom Quote
We write the methodology, evidence synthesis, and study design sections of your NIH, NIHR, or institutional grant proposal, including protocol development and preliminary literature review.
What's Included
- Methodology section writing (study design, analysis plan)
- Protocol development (PRISMA-P) for systematic review grants
- PROSPERO submission preparation
- Preliminary literature search & evidence gap analysis
- Statistical analysis plan with power calculations
- Figures, flow diagrams, and timeline graphics
Typical timeline: 2 - 4 weeks
Response-to-Reviewers Drafting
Custom Quote
Got a revise-and-resubmit? We draft a professional point-by-point response letter and revise your manuscript to address every reviewer comment, so you resubmit with confidence.
What's Included
- Point-by-point response letter addressing every comment
- Revised manuscript with tracked changes
- Additional statistical analyses if requested by reviewers
- Updated figures, tables, and supplementary materials
- Diplomatic, professional tone throughout
- Final proofread and journal formatting check
Typical timeline: 1 - 2 weeks
Manuscript Editing
Custom Quote
Every manuscript is matched with a subject-matter editor published in your field, then read independently by a senior second editor before it goes back to you, in a two-pass workflow built for journal submission.
What's Included
- Subject-matter editor plus a senior second reader
- Language, structure, argument, and compliance layers
- Reporting guideline checks (CONSORT, STROBE, PRISMA)
- Target journal formatting and style compliance
- Two-pass editorial workflow
- Confidential handling under non-disclosure agreement
Academic Editing
Custom Quote
Substantive editing, copy editing, and proofreading by native-English PhD editors, matched to the stage your draft is actually at. Theses, dissertations, conference papers, book chapters, and research proposals.
What's Included
- Three editing depths matched to your draft's stage
- Theses, dissertations, chapters, and proposals
- Dedicated support for non-native English authors
- Editor matched to your discipline
- Priced per source word, quoted before work starts
- Rush turnaround available when you are against a deadline
Grant Writing
Custom Quote
Full grant applications drafted for National Institutes of Health, National Institute for Health and Care Research, and institutional funders, written to the funder's scoring rubric and mock-reviewed before you submit.
What's Included
- Specific aims, significance, innovation, and approach
- Every scored section written to the funder's rubric
- Mock review by former study section reviewers
- Budget justification and supporting documents
- Revisions through to submission
- Fixed quote returned within 24 hours
Research Consultant
Custom Quote
A PhD methodologist matched to your field to scope your study, design the methodology, set the analysis plan, and shape the reporting, engaged either hourly or on a fixed scope.
What's Included
- Study design and sampling strategy
- Methodology chapter and analysis plan
- Methodology input for grants and protocols
- Hourly or fixed-scope engagement
- Consultant matched to your discipline
- Reporting and write-up support
Medical Translation
Custom Quote
Manuscripts, study protocols, questionnaires, and theses translated by subject-specialist linguists in a two-translator workflow, certified where journals require it.
What's Included
- Manuscripts, protocols, questionnaires, and theses
- Two-translator workflow with independent review
- Arabic and English in both directions, our deepest pair
- Twelve language pairs across major research languages
- Certification for journal and institutional submission
- Confidential handling under non-disclosure agreement
Data, Survey & Bioinformatics Analysis
Data visualization, survey data analysis, and bioinformatics analysis for researchers. Reproducible code, publication-ready figures, and a results section written for your journal or thesis.
Data Visualization Service
Custom Quote
Publication-quality figures and scientific data visualization for journals, theses, and grants. We turn your raw data into clear, accurate charts built in ggplot2, Python, or GraphPad Prism, with editable source files and journal-compliant formatting.
What's Included
- Forest plots, heatmaps, box plots, survival curves, and custom figures
- Colorblind-safe palettes and journal figure specifications
- Vector (PDF, EPS) and high-resolution (TIFF, PNG) output
- Editable ggplot2, Python, or Prism source files
- Figure legends drafted for your manuscript
- Free redraws until reviewers accept the visuals
Typical timeline: 3 days - 2 weeks
Survey Data Analysis
Custom Quote
Survey data analysis for questionnaires, Likert scales, and validated instruments. PhD statisticians clean your data, validate your scales, and run the analysis in R, SPSS, or Stata, with a results section written for your thesis or target journal.
What's Included
- Data cleaning, recoding, and missing-data handling
- Reliability (Cronbach's alpha) and factor analysis
- Descriptive, comparative, and regression analysis
- Publication-ready tables and figures
- Results-section prose for your write-up
- Reproducible R, SPSS, or Stata syntax
Typical timeline: 3 days - 2 weeks
Bioinformatics Analysis Service
Custom Quote
End-to-end bioinformatics analysis for RNA sequencing, whole genome sequencing, single-cell, and metagenomics. PhD bioinformaticians run reproducible Bioconda or Nextflow pipelines from raw reads to publication figures, with full methods text and code.
What's Included
- Read quality control, trimming, and preprocessing
- RNA-seq, WGS, single-cell, and metagenomics pipelines
- Differential expression, variant calling, and phylogenetics
- Publication-ready figures and statistics
- Methods text with exact tools and versions
- Reproducible pipeline and code at handoff
Typical timeline: 1 - 4 weeks
Hire a Statistician
Custom Quote
Bring in a PhD statistician by the project or the hour. We choose the right analysis, run it in R, SPSS, Stata, or SAS, and return reproducible code with a written interpretation you can defend in peer review or a viva.
What's Included
- Subject-matched PhD statistician
- Study design and analysis-plan advice
- Statistical test selection matched to your design
- Annotated, reproducible code in your software
- Publication-ready tables and figures
- Written walkthrough of every result
Typical timeline: 3 days - 3 weeks
Data Analysis Service
Custom Quote
Done-for-you data analysis from raw file to written report. PhD analysts clean your data, run the right statistical analysis in R, Python, SPSS, or Stata, and deliver figures and a plain-language interpretation for academic, clinical, or business datasets.
What's Included
- Data cleaning, recoding, and missing-data strategy
- Statistical analysis matched to your question
- Exploratory analysis and visualization
- Publication or report-ready tables and figures
- Written report interpreting every result
- Reproducible R, Python, SPSS, or Stata code
Typical timeline: 3 days - 3 weeks
Clinical Data Management
Custom Quote
Clinical and research data management from data management plan to database lock. We design case report forms, build validated study databases, clean and query the data, and hand back a CDISC-aware, analysis-ready dataset with a full audit trail.
What's Included
- Data management plan and annotated data dictionary
- Case report form or eCRF design
- Validated database with edit checks and controlled terminology
- Data cleaning and documented query management
- Medical and drug coding (MedDRA, WHODrug) where required
- CDISC-aware dataset and database-lock documentation
Typical timeline: Custom (project or institutional)
Dissertation Statistics Help
Custom Quote
A dissertation lives or dies on Chapter 4. PhD methodologists select the right test, run the analysis in SPSS, R, or Stata, and hand back a results chapter your committee can defend.
What's Included
- Statistical test selection, justified in writing
- Analysis run in SPSS, R, or Stata
- Results chapter written and interpreted
- Assumption checks documented throughout
- Tables and figures formatted to your style guide
- Defense preparation and committee revisions
Statistical Consulting
Custom Quote
A statistician on call from first design to final submission, for when you need the design confirmed before you collect data or a model sanity-checked because a reviewer is questioning it.
What's Included
- Study design review before data collection
- Sample size and power calculations
- Model specification and test selection
- Second-opinion review before you submit
- Reviewer statistical queries answered
- Advisory sessions or a full review engagement
Qualitative Data Analysis
Custom Quote
Thematic, framework, grounded theory, and content coding run in NVivo, MAXQDA, or ATLAS.ti by a PhD researcher published in your field and methodological tradition.
What's Included
- Coding in NVivo, MAXQDA, or ATLAS.ti
- Thematic, framework, grounded theory, or content analysis
- Codebook development and audit trail
- Themes written up for your thesis or manuscript
- Project file delivered so the coding is reproducible
- Analyst matched to your field and tradition
Review Components & Institutional Evidence Synthesis
Order individual systematic review components, or commission submission-grade reviews for health technology assessment, market access, and regulatory dossiers. Available standalone or as part of a full review, with non-disclosure agreements for institutional work.
Protocol & PROSPERO Registration
Custom Quote
An a priori systematic review protocol written to PRISMA-P 2015, with a completed PROSPERO record you file under your own account so you remain the registrant and author.
What's Included
- Full PRISMA-P 2015 protocol document
- PICO or PICOS question with eligibility criteria
- Planned search, screening, and extraction methods
- Risk-of-bias and GRADE certainty plan
- Completed PROSPERO record for you to submit
- Version-controlled amendments if the protocol changes
Typical timeline: 3 days - 2 weeks
Search Strategy Development
Custom Quote
Reproducible, database-specific search strategies built and peer-reviewed to PRESS and documented for the PRISMA-S extension, so your search is defensible and re-runnable.
What's Included
- Strategies for MEDLINE, Embase, CENTRAL, CINAHL, and more
- Controlled vocabulary (MeSH, Emtree) and free-text terms
- PRESS peer review by an information specialist
- Grey literature and trials-register searching
- Deduplicated, import-ready results
- Full PRISMA-S search documentation
Typical timeline: 3 days - 1 week
HTA & Market Access Evidence Synthesis
Custom Quote
PICOS-driven systematic literature reviews for health technology assessment and market access, aligned to NICE, CADTH, ICER, and G-BA, formatted for your value dossier.
What's Included
- Clinical, economic, and patient-reported-outcome reviews
- Peer-reviewed search across clinical and economic databases
- Dual-reviewer screening and evidence tables
- AMSTAR 2 appraisal and risk-of-bias assessment
- Indirect comparison or network meta-analysis where relevant
- Non-disclosure agreements and purchase orders on request
Typical timeline: Custom (institutional)
Pharmaceutical & Regulatory Reviews
Custom Quote
Audit-ready structured literature reviews for regulatory submissions, including Clinical Evaluation Report reviews under EU MDR and MEDDEV 2.7/1, and safety literature reviews under GVP.
What's Included
- Pre-specified, audit-ready review protocol
- Fully documented, reproducible literature search
- Structured screening and appraisal tables
- Clinical Evaluation Report and safety-review synthesis
- Inspection-ready audit trail from protocol to report
- Non-disclosure agreements and purchase orders on request
Typical timeline: Custom (institutional)
Evidence Synthesis Services
Custom Quote
One methodology team across every review format, matched to your question rather than bent to fit a single house method. Umbrella reviews, rapid reviews, scoping reviews, and living reviews, all held to GRADE and AMSTAR 2 standards.
What's Included
- Review-type selection matched to your research question
- Umbrella reviews of existing systematic reviews
- Rapid reviews on a compressed evidence timeline
- Living reviews with scheduled update cycles
- GRADE certainty ratings and AMSTAR 2 appraisal
- Fixed project quote before any work begins
Literature Review Writing
Custom Quote
Narrative literature reviews written for thesis chapters, journal introductions, and grant backgrounds, delivered as a complete bundle you can drop straight into your document, with the search documented and reproducible.
What's Included
- Documented, reproducible search across your field's databases
- Thesis chapter, journal introduction, or grant background
- Thematic structure with a defensible synthesis narrative
- Your citation style, formatted throughout
- Reference manager library delivered with the draft
- Writer matched to your field and published in it
Pharmacovigilance Literature Screening
Custom Quote
Scheduled worldwide literature monitoring for marketed products under Good Pharmacovigilance Practices Module VI, with dual independent review and an audit trail built for inspection.
What's Included
- Documented search strategy on your defined cadence
- Local and global literature coverage
- Dual independent reviewer screening
- Valid case identification and flagging
- Quality control checks at every stage
- Inspection-ready audit records
Typical timeline: Custom (institutional)
Nursing & Clinical Practice
Care plans, clinical documentation, evidence-based practice projects, and capstones, written by clinicians to your programme rubric. Human-written, with the reasoning shown.
Doctoral Nursing Practice Project
Custom Quote
The full scholarly project for a practice doctorate: we define the practice problem, frame the PICOT-D question, select and apply the implementation framework your programme expects, synthesise the evidence, and design an evaluation with outcomes your site can actually measure.
What's Included
- PICOT-D question and defined local practice problem
- Implementation framework selected and justified (Iowa, Johns Hopkins, Stetler, ACE Star, PARIHS)
- Structured CINAHL, PubMed, and Cochrane search, documented and reproducible
- Critical appraisal with CASP or JBI, reasoning written out
- Evidence summary tables with levels of evidence assigned
- Implementation plan with Plan-Do-Study-Act cycles specified
- Evaluation design, reproducible analysis, and SQUIRE 2.0 reporting
Typical timeline: 4 to 10 weeks (varies by scope)
Capstone Project
Custom Quote
Capstone support at bachelor’s, master’s, and doctoral level, built to the rubric your programme grades against. We check the level against your rubric first, because writing at the wrong scope is the most common and most expensive capstone error.
What's Included
- Level checked against your programme rubric before anything is written
- Focused clinical question, framed in PICOT where required
- Documented search across CINAHL, PubMed, and Cochrane
- Critical appraisal using CASP or JBI with the reasoning shown
- Evidence summary tables and APA 7 referencing
- Theoretical or evidence-based practice framework where the rubric requires one
- Reproducible statistics and interpretation where an outcome is measured
Typical timeline: 2 to 6 weeks (varies by level)
Nursing Dissertation
Custom Quote
Chapter-by-chapter support for a nursing dissertation, from settling the research question through the evidence review, methods, results, and discussion, with the rationale written as we go so you can defend every decision in a viva.
What's Included
- Research question settled and the design rationale written
- Reproducible search across CINAHL, PubMed, and Cochrane
- Evidence review written as a synthesis, not a list of studies
- Methods chapter justifying each choice against the question
- Reproducible analysis in R, SPSS, Stata, NVivo, or MAXQDA
- Discussion stating limitations honestly
- Viva preparation from the rationale built during the work
Typical timeline: Custom (single chapter or full dissertation)
Nursing Writing
Custom Quote
Graduate nursing work judged on method, not just prose. Doctor of Nursing Practice projects, nursing dissertations, and evidence-based practice projects with a defensible clinical question, sound design, and correctly run analysis.
What's Included
- Doctor of Nursing Practice and capstone project support
- Nursing dissertations and evidence-based practice projects
- Evidence-based practice models applied correctly
- Care plans and clinical documentation
- Nursing research papers and case studies
- Human-written, original work throughout
Nursing Care Plan Writing
Custom Quote
Care plans built on NANDA-I diagnoses written in PES format, with measurable NOC outcomes and NIC interventions that each carry an evidence rationale, formatted to your programme's template.
What's Included
- Assessment data organised into subjective and objective findings
- NANDA-I diagnoses in PES format, prioritised with a stated rationale
- Measurable NOC outcomes with target timeframes
- NIC interventions each carrying an evidence rationale
- An evaluation section written against the stated outcomes
- Written to your programme's care plan template
SOAP Note Documentation
Custom Quote
Clinical documentation in subjective, objective, assessment, and plan format, with the assessment committing to a working diagnosis and naming the differentials considered, so it survives preceptor review.
What's Included
- Subjective and objective sections separated cleanly
- A working assessment with the differentials considered
- A plan covering diagnostics, treatment, education, and follow-up
- Clinical reasoning made explicit for preceptor review
- SOAP, APSO, or DAP format as your programme requires
- Written to your programme or clinical template
Evidence-Based Practice and PICOT Projects
Custom Quote
Evidence-based practice projects built from a searchable PICOT question through to an implementation and evaluation plan, under the Johns Hopkins or Iowa model your programme mandates.
What's Included
- A searchable PICOT question agreed before searching begins
- Documented, reproducible search across CINAHL and PubMed
- Appraisal tables with levels of evidence assigned
- A synthesis stating what the evidence does and does not support
- An implementation plan naming stakeholders and barriers
- An evaluation plan with a measurable outcome
Nursing Theory and Concept Analysis
Custom Quote
Concept analyses written with the Walker and Avant eight-step method, with defining attributes derived from the literature and model, borderline, and contrary cases constructed to test them.
What's Included
- A literature map of how the concept is used across disciplines
- Defining attributes established from the evidence
- Model, borderline, and contrary cases
- Antecedents, consequences, and empirical referents
- The theoretical framework linkage made explicit
- Walker and Avant, Rodgers, or the method your rubric names
Healthcare Case Study Writing
Custom Quote
Clinical case studies for coursework or journal submission, built around a clear clinical timeline and discussed against published literature, reported to the CARE guidelines where publication is the aim.
What's Included
- A structured clinical timeline of the case
- Presentation, history, and diagnostic findings written up
- Discussion situating the case against published literature
- CARE-guideline-compliant reporting for publication
- Consent and de-identification handled correctly
- Journal selection advice where you intend to submit
Add-On Services
Customize your project with optional enhancements. Add-ons are priced into your quote up front, before you commit.
Popular
Rush Delivery
Priority scheduling with a dedicated team, reducing turnaround by up to 50%. Ideal for grant deadlines, thesis submissions, and time-sensitive publications.
Network Meta-Analysis & Advanced Analyses
Network meta-analysis service, dose-response analysis, cumulative meta-analysis, or umbrella review service. Specialized analyses beyond the standard package.
Recommended
GRADE Assessment
Formal assessment of evidence certainty using the GRADE framework. Includes summary of findings tables, increasingly required by Q1 journals and Cochrane.
Search Strategy Only
A standalone, peer-reviewed search strategy across your chosen databases (PubMed, Embase, Cochrane, Scopus, and more), fully documented and ready for you to execute independently.
Your Project Is Protected
Every project includes these guarantees, regardless of tier or scope.
Human PhD Methodologists
A methodologist makes every judgment call
Deadline Commitment
We agree your deadline in writing before you pay
Unlimited Revisions
Revise until you and your reviewers are satisfied
NDA on Request
Confidential by default; mutual NDA available on request
Your Methods Are the First Thing Reviewers Read. Make Them Count.
Systematic review writing, biostatistics consulting, medical manuscript drafting, or response-to-reviewers, describe your project and a named PhD methodologist will reply with an itemized quote within a few hours. Unlimited revisions within your agreed scope.